Drug interactions
Betaxolol + Valsartan
Severity: Moderate
Betaxolol and Valsartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol and valsartan produce additive blood pressure lowering, and hypotension may occur at initiation or with volume depletion. Both may contribute modestly to higher serum potassium.
What this interaction means in plain words
Betaxolol and Valsartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Valsartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects, with angiotensin receptor blockade reducing aldosterone and beta-blockade impairing cellular potassium uptake.
What to do
Monitor blood pressure and serum potassium, particularly in renal impairment or heart failure. Valsartan should be avoided in pregnancy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Other interactions of Valsartan
- Aliskiren + Valsartan Contraindicated
- Sparsentan + Valsartan Contraindicated
- Aldesleukin + Valsartan Major
- Amifostine + Valsartan Major
- Amiloride + Valsartan Major
- Amlodipine-benazepril + Valsartan Major
Frequently asked questions
Can I take Betaxolol with Valsartan?
MediHelp rates the interaction as moderate. Betaxolol and Valsartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Betaxolol and valsartan produce additive blood pressure lowering, and hypotension may occur at initiation or with volume depletion. Both may contribute modestly to higher serum potassium.
How serious is the interaction between Betaxolol and Valsartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum potassium, particularly in renal impairment or heart failure. Valsartan should be avoided in pregnancy.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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