Drug interactions
Bisoprolol + Dipyridamole
Severity: Minor
Bisoprolol and Dipyridamole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole increases adenosine levels and can have mild effects on heart rate and conduction, and bisoprolol also slows conduction. Bradycardia is possible, particularly during pharmacologic stress testing.
What this interaction means in plain words
Bisoprolol and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bisoprolol belongs to Cardiovascular; Dipyridamole belongs to Cardiovascular.
Why it happens
Dipyridamole blocks adenosine reuptake, enhancing adenosine-mediated nodal slowing on top of beta-blockade.
What to do
Monitor heart rate and ECG during intravenous dipyridamole stress testing in patients on bisoprolol. No change is generally needed with oral maintenance therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bisoprolol
Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Frequently asked questions
Can I take Bisoprolol with Dipyridamole?
MediHelp rates the interaction as minor. Bisoprolol and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dipyridamole increases adenosine levels and can have mild effects on heart rate and conduction, and bisoprolol also slows conduction. Bradycardia is possible, particularly during pharmacologic stress testing.
How serious is the interaction between Bisoprolol and Dipyridamole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and ECG during intravenous dipyridamole stress testing in patients on bisoprolol. No change is generally needed with oral maintenance therapy.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
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