Drug interactions
Bisoprolol + Eprosartan
Severity: Moderate
Bisoprolol and Eprosartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination yields additive blood pressure reduction that may cause symptomatic hypotension, mostly at initiation. Eprosartan is fetotoxic in pregnancy.
What this interaction means in plain words
Bisoprolol and Eprosartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bisoprolol belongs to Cardiovascular; Eprosartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effect from beta-blockade and angiotensin II receptor blockade.
What to do
Monitor blood pressure and heart rate when starting or adjusting doses, and stop eprosartan if pregnancy occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bisoprolol
Other interactions of Eprosartan
- Aliskiren + Eprosartan Contraindicated
- Eprosartan + Sparsentan Contraindicated
- Amifostine + Eprosartan Major
- Amiloride + Eprosartan Major
- Amlodipine-benazepril + Eprosartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Eprosartan Major
Frequently asked questions
Can I take Bisoprolol with Eprosartan?
MediHelp rates the interaction as moderate. Bisoprolol and Eprosartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The combination yields additive blood pressure reduction that may cause symptomatic hypotension, mostly at initiation. Eprosartan is fetotoxic in pregnancy.
How serious is the interaction between Bisoprolol and Eprosartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting doses, and stop eprosartan if pregnancy occurs.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
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