Drug interactions
Bitter melon + Eprosartan-hydrochlorothiazide
Severity: Minor
Bitter melon and Eprosartan-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bitter melon has been associated with lowering of blood glucose and possibly potassium, and may add to thiazide-related hypokalemia. Evidence is limited to theoretical and small reports.
What this interaction means in plain words
Bitter melon and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive potassium loss; mechanism not clearly established.
What to do
Check serum potassium periodically if bitter melon is used regularly alongside the thiazide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Bitter melon with Eprosartan-hydrochlorothiazide?
MediHelp rates the interaction as minor. Bitter melon and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bitter melon has been associated with lowering of blood glucose and possibly potassium, and may add to thiazide-related hypokalemia. Evidence is limited to theoretical and small reports.
How serious is the interaction between Bitter melon and Eprosartan-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium periodically if bitter melon is used regularly alongside the thiazide.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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