Drug interactions
Brivaracetam + Imipramine
Severity: Minor
Brivaracetam and Imipramine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brivaracetam frequently causes somnolence and dizziness, and imipramine is also sedating. Combined use may cause additive drowsiness and reduced alertness. Tricyclics may also lower the seizure threshold.
What this interaction means in plain words
Brivaracetam and Imipramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brivaracetam belongs to Central Nervous System; Imipramine belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Counsel about additive drowsiness and driving risk. Monitor seizure control and adjust doses if sedation is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Imipramine
- Dronedarone + Imipramine Contraindicated
- Imipramine + Isocarboxazid Contraindicated
- Imipramine + Phenelzine Contraindicated
- Imipramine + Pimozide Contraindicated
- Imipramine + Rasagiline Contraindicated
- Imipramine + Safinamide Contraindicated
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Imipramine?
MediHelp rates the interaction as minor. Brivaracetam and Imipramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brivaracetam frequently causes somnolence and dizziness, and imipramine is also sedating. Combined use may cause additive drowsiness and reduced alertness. Tricyclics may also lower the seizure threshold.
How serious is the interaction between Brivaracetam and Imipramine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel about additive drowsiness and driving risk. Monitor seizure control and adjust doses if sedation is troublesome.
What other medicines interact with Imipramine?
MediHelp also lists interactions of Imipramine with, for example, Dronedarone, Isocarboxazid, Phenelzine. The full list is on the Imipramine page.
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