Drug interactions
Budesonide + Eprosartan-hydrochlorothiazide
Severity: Minor
Budesonide and Eprosartan-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic glucocorticoids and thiazides both promote potassium loss, so hypokalemia may be additive. With oral or inhaled budesonide systemic exposure is lower, so the risk is smaller than with prednisone-type steroids.
What this interaction means in plain words
Budesonide and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Eprosartan-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Additive renal potassium wasting from thiazide action and glucocorticoid mineralocorticoid activity.
What to do
Check serum potassium if budesonide is used at high doses or for prolonged courses along with the thiazide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Eprosartan-hydrochlorothiazide?
MediHelp rates the interaction as minor. Budesonide and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic glucocorticoids and thiazides both promote potassium loss, so hypokalemia may be additive. With oral or inhaled budesonide systemic exposure is lower, so the risk is smaller than with prednisone-type steroids.
How serious is the interaction between Budesonide and Eprosartan-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium if budesonide is used at high doses or for prolonged courses along with the thiazide.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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