Drug interactions
Budesonide + Fingolimod
Severity: Moderate
Budesonide and Fingolimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents suppress immune function, so combined use may increase the risk of infection. Systemic exposure to budesonide is greater with oral or high-dose use and with CYP3A4 inhibitors.
What this interaction means in plain words
Budesonide and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide belongs to Respiratory; Fingolimod belongs to Central Nervous System.
Why it happens
Additive immunosuppression from lymphocyte sequestration by fingolimod and glucocorticoid effects.
What to do
Monitor for signs of infection and avoid prolonged systemic corticosteroid courses when possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Budesonide with Fingolimod?
MediHelp rates the interaction as moderate. Budesonide and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents suppress immune function, so combined use may increase the risk of infection. Systemic exposure to budesonide is greater with oral or high-dose use and with CYP3A4 inhibitors.
How serious is the interaction between Budesonide and Fingolimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection and avoid prolonged systemic corticosteroid courses when possible.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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