Drug interactions
Budesonide + Gliclazide
Severity: Minor
Budesonide and Gliclazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Budesonide can raise blood glucose, mainly with oral or high-dose use, which may reduce the effectiveness of gliclazide. Inhaled or locally acting formulations have limited systemic effect.
What this interaction means in plain words
Budesonide and Gliclazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Gliclazide belongs to Endocrine.
Why it happens
Glucocorticoid-induced insulin resistance and increased hepatic glucose output opposing the sulfonylurea.
What to do
Monitor blood glucose when starting systemic budesonide or at high doses, and adjust gliclazide if hyperglycemia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gliclazide
Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Gliclazide?
MediHelp rates the interaction as minor. Budesonide and Gliclazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Budesonide can raise blood glucose, mainly with oral or high-dose use, which may reduce the effectiveness of gliclazide. Inhaled or locally acting formulations have limited systemic effect.
How serious is the interaction between Budesonide and Gliclazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting systemic budesonide or at high doses, and adjust gliclazide if hyperglycemia develops.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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