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Drug interactions

Budesonide + Hydrochlorothiazide-telmisartan

Severity: Minor

Budesonide and Hydrochlorothiazide-telmisartan: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Corticosteroids and thiazide diuretics both promote potassium loss, so combined use may cause hypokalemia. The risk is greater with systemic exposure and less with locally acting budesonide formulations.

What this interaction means in plain words

Budesonide and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Budesonide belongs to Respiratory; Hydrochlorothiazide-telmisartan belongs to Cardiovascular.

Evidence level: Moderate

Why it happens

Additive renal potassium wasting from thiazide action and corticosteroid mineralocorticoid effect.

What to do

Monitor serum potassium, particularly with systemic or high-dose budesonide, and supplement potassium if needed. Telmisartan may partly offset the loss.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide with Hydrochlorothiazide-telmisartan?

MediHelp rates the interaction as minor. Budesonide and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids and thiazide diuretics both promote potassium loss, so combined use may cause hypokalemia. The risk is greater with systemic exposure and less with locally acting budesonide formulations.

How serious is the interaction between Budesonide and Hydrochlorothiazide-telmisartan?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium, particularly with systemic or high-dose budesonide, and supplement potassium if needed. Telmisartan may partly offset the loss.

What other medicines interact with Hydrochlorothiazide-telmisartan?

MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.

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