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Drug interactions

Budesonide + Nateglinide

Severity: Minor

Budesonide and Nateglinide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Budesonide can raise blood glucose and lessen the glucose-lowering effect of nateglinide. The clinical impact depends on the budesonide dose and route, and is small with inhaled use.

What this interaction means in plain words

Budesonide and Nateglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Budesonide belongs to Respiratory; Nateglinide belongs to Endocrine.

Evidence level: Moderate

Why it happens

Pharmacodynamic antagonism through corticosteroid-induced hyperglycemia and insulin resistance.

What to do

Monitor blood glucose during and after budesonide therapy and increase the antidiabetic dose if needed. Watch for hypoglycemia when the steroid is withdrawn.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide with Nateglinide?

MediHelp rates the interaction as minor. Budesonide and Nateglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Budesonide can raise blood glucose and lessen the glucose-lowering effect of nateglinide. The clinical impact depends on the budesonide dose and route, and is small with inhaled use.

How serious is the interaction between Budesonide and Nateglinide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during and after budesonide therapy and increase the antidiabetic dose if needed. Watch for hypoglycemia when the steroid is withdrawn.

What other medicines interact with Budesonide?

MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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