Drug interactions
Budesonide + Nifedipine
Severity: Minor
Budesonide and Nifedipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nifedipine is a CYP3A4 substrate with little inhibitory activity, so a significant change in budesonide exposure is unlikely. Clinical relevance is minimal.
What this interaction means in plain words
Budesonide and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Nifedipine belongs to Cardiovascular.
Why it happens
Possible minor competition for CYP3A4 and P-glycoprotein; not clinically established.
What to do
No action is needed beyond routine monitoring of blood pressure and corticosteroid effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Nifedipine
Frequently asked questions
Can I take Budesonide with Nifedipine?
MediHelp rates the interaction as minor. Budesonide and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nifedipine is a CYP3A4 substrate with little inhibitory activity, so a significant change in budesonide exposure is unlikely. Clinical relevance is minimal.
How serious is the interaction between Budesonide and Nifedipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed beyond routine monitoring of blood pressure and corticosteroid effects.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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