Drug interactions
Buprenorphine long-acting + Foscarnet
Severity: Moderate
Buprenorphine long-acting and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can influence QT interval, and long-acting buprenorphine gives sustained exposure that cannot be quickly withdrawn. Foscarnet's electrolyte disturbances may add to the risk of arrhythmia.
What this interaction means in plain words
Buprenorphine long-acting and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive QT prolongation with foscarnet-induced electrolyte disturbances.
What to do
Monitor the ECG and electrolytes during foscarnet therapy, correcting any abnormality. Consider extra monitoring if the patient has other QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Buprenorphine long-acting with Foscarnet?
MediHelp rates the interaction as moderate. Buprenorphine long-acting and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can influence QT interval, and long-acting buprenorphine gives sustained exposure that cannot be quickly withdrawn. Foscarnet's electrolyte disturbances may add to the risk of arrhythmia.
How serious is the interaction between Buprenorphine long-acting and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the ECG and electrolytes during foscarnet therapy, correcting any abnormality. Consider extra monitoring if the patient has other QT risk factors.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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