Drug interactions
Buprenorphine subdermal implant + Foscarnet
Severity: Minor
Buprenorphine subdermal implant and Foscarnet: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can affect cardiac repolarization, although the implant gives low, steady buprenorphine exposure. Foscarnet's electrolyte disturbances may still add to the arrhythmia risk.
What this interaction means in plain words
Buprenorphine subdermal implant and Foscarnet have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive QT prolongation, with foscarnet electrolyte shifts.
What to do
Monitor electrolytes during foscarnet therapy and obtain an ECG if the patient has other QT risk factors or symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Buprenorphine subdermal implant with Foscarnet?
MediHelp rates the interaction as minor. Buprenorphine subdermal implant and Foscarnet have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can affect cardiac repolarization, although the implant gives low, steady buprenorphine exposure. Foscarnet's electrolyte disturbances may still add to the arrhythmia risk.
How serious is the interaction between Buprenorphine subdermal implant and Foscarnet?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor electrolytes during foscarnet therapy and obtain an ECG if the patient has other QT risk factors or symptoms.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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