Drug interactions
Buprenorphine transdermal + Sunitinib
Severity: Moderate
Buprenorphine transdermal and Sunitinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Transdermal buprenorphine has QT prolongation warnings and sunitinib also prolongs QT. Together the risk of arrhythmia is higher.
What this interaction means in plain words
Buprenorphine transdermal and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation.
What to do
Monitor ECG and electrolytes and use the lowest effective patch strength.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Frequently asked questions
Can I take Buprenorphine transdermal with Sunitinib?
MediHelp rates the interaction as moderate. Buprenorphine transdermal and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Transdermal buprenorphine has QT prolongation warnings and sunitinib also prolongs QT. Together the risk of arrhythmia is higher.
How serious is the interaction between Buprenorphine transdermal and Sunitinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes and use the lowest effective patch strength.
What other medicines interact with Sunitinib?
MediHelp also lists interactions of Sunitinib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Sunitinib page.
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