Drug interactions
Buprenorphine transdermal + Telavancin
Severity: Moderate
Buprenorphine transdermal and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telavancin may modestly prolong the QT interval, and transdermal buprenorphine carries labeled QT prolongation warnings at higher doses. Together they may add to the risk of torsades de pointes in susceptible patients.
What this interaction means in plain words
Buprenorphine transdermal and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic QT prolongation affecting cardiac repolarization.
What to do
Get a baseline ECG and correct potassium and magnesium abnormalities. Monitor the QTc, and consider a lower patch strength or an alternative antibiotic if the QTc lengthens significantly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Frequently asked questions
Can I take Buprenorphine transdermal with Telavancin?
MediHelp rates the interaction as moderate. Buprenorphine transdermal and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Telavancin may modestly prolong the QT interval, and transdermal buprenorphine carries labeled QT prolongation warnings at higher doses. Together they may add to the risk of torsades de pointes in susceptible patients.
How serious is the interaction between Buprenorphine transdermal and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Get a baseline ECG and correct potassium and magnesium abnormalities. Monitor the QTc, and consider a lower patch strength or an alternative antibiotic if the QTc lengthens significantly.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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