Drug interactions
Telavancin + Thioridazine
Severity: Contraindicated
Telavancin and Thioridazine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thioridazine causes marked, dose-related QTc prolongation and has a boxed warning for torsades de pointes. Adding telavancin may further increase the risk of fatal arrhythmia.
What this interaction means in plain words
Telavancin and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Telavancin belongs to Anti Bacterial; Thioridazine belongs to Central Nervous System.
Why it happens
Additive prolongation of ventricular repolarization on a background of marked QT effect from thioridazine.
What to do
Avoid co-administration and select a non-QT-prolonging antibiotic. If thioridazine cannot be stopped, use an alternative antibacterial.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Telavancin
Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Frequently asked questions
Can I take Telavancin with Thioridazine?
MediHelp rates the interaction as contraindicated. Telavancin and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Thioridazine causes marked, dose-related QTc prolongation and has a boxed warning for torsades de pointes. Adding telavancin may further increase the risk of fatal arrhythmia.
How serious is the interaction between Telavancin and Thioridazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid co-administration and select a non-QT-prolonging antibiotic. If thioridazine cannot be stopped, use an alternative antibacterial.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Telavancin page.
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