Drug interactions
Calcium citrate + Prednisolone
Severity: Minor
Calcium citrate and Prednisolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Long-term corticosteroid use impairs calcium absorption and promotes urinary calcium loss, partly counteracting calcium supplements. This matters mainly for bone health during prolonged therapy.
What this interaction means in plain words
Calcium citrate and Prednisolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucocorticoids decrease intestinal calcium absorption and increase renal calcium excretion.
What to do
Continue calcium with vitamin D during chronic steroid therapy and monitor bone health as indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisolone
- Bcg vaccine live + Prednisolone Contraindicated
- Measles mumps and rubella vaccine live + Prednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicated
- Measles vaccine + Prednisolone Contraindicated
- Mifepristone + Prednisolone Contraindicated
- Prednisolone + Radium-223 dichloride Contraindicated
Frequently asked questions
Can I take Calcium citrate with Prednisolone?
MediHelp rates the interaction as minor. Calcium citrate and Prednisolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Long-term corticosteroid use impairs calcium absorption and promotes urinary calcium loss, partly counteracting calcium supplements. This matters mainly for bone health during prolonged therapy.
How serious is the interaction between Calcium citrate and Prednisolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue calcium with vitamin D during chronic steroid therapy and monitor bone health as indicated.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
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