Drug interactions
Canagliflozin-metformin + Citalopram
Severity: Minor
Canagliflozin-metformin and Citalopram: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
SSRIs may modestly improve or alter glucose control, and hypoglycemia has been reported when they are added to antidiabetic therapy. The effect is usually small and variable between patients.
What this interaction means in plain words
Canagliflozin-metformin and Citalopram have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Canagliflozin-metformin belongs to Endocrine; Citalopram belongs to Central Nervous System.
Why it happens
The mechanism is not well established; SSRIs may alter insulin sensitivity and glucose counterregulation.
What to do
Check blood glucose more often when starting or stopping citalopram and adjust antidiabetic therapy only if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Canagliflozin-metformin and Citalopram, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Canagliflozin-metformin
Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Canagliflozin-metformin with Citalopram?
MediHelp rates the interaction as minor. Canagliflozin-metformin and Citalopram have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. SSRIs may modestly improve or alter glucose control, and hypoglycemia has been reported when they are added to antidiabetic therapy. The effect is usually small and variable between patients.
How serious is the interaction between Canagliflozin-metformin and Citalopram?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more often when starting or stopping citalopram and adjust antidiabetic therapy only if control changes.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
