Drug reference
canagliflozin-metformin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Glycosurics)
Mechanism of action
Canagliflozin: Selective sodium-glucose transporter-2 (SGLT2) inhibitor; SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose.
Common side effects
- Flatulence
- Vomiting
- Nausea
- Female genital mycotic infections
- Diarrhea
Related conditions
Frequently asked questions
What drug class is canagliflozin-metformin?
canagliflozin-metformin belongs to: Endocrine.
How does canagliflozin-metformin work?
Canagliflozin: Selective sodium-glucose transporter-2 (SGLT2) inhibitor; SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose.
What are the common side effects of canagliflozin-metformin?
Flatulence, Vomiting, Nausea, Female genital mycotic infections, Diarrhea
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.