Drug interactions
Canagliflozin-metformin + Maitake
Severity: Minor
Canagliflozin-metformin and Maitake: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maitake mushroom extracts have lowered blood glucose in animal studies, so they might add to the effect of metformin and canagliflozin. Human data are scarce and the clinical relevance is uncertain.
What this interaction means in plain words
Canagliflozin-metformin and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive glucose-lowering effect, shown only in animal data; the mechanism is not established in humans.
What to do
Advise patients to tell their clinician if they use maitake supplements and monitor home glucose readings. Reduce antidiabetic doses only if hypoglycemia or unexpectedly low readings occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Canagliflozin-metformin and Maitake, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Canagliflozin-metformin
Frequently asked questions
Can I take Canagliflozin-metformin with Maitake?
MediHelp rates the interaction as minor. Canagliflozin-metformin and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom extracts have lowered blood glucose in animal studies, so they might add to the effect of metformin and canagliflozin. Human data are scarce and the clinical relevance is uncertain.
How serious is the interaction between Canagliflozin-metformin and Maitake?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to tell their clinician if they use maitake supplements and monitor home glucose readings. Reduce antidiabetic doses only if hypoglycemia or unexpectedly low readings occur.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
