Drug interactions
Canagliflozin-metformin + Norgestimate
Severity: Minor
Canagliflozin-metformin and Norgestimate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Norgestimate, usually given with an estrogen in contraceptives, can slightly reduce glucose tolerance. The effect on diabetes control is usually small.
What this interaction means in plain words
Canagliflozin-metformin and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Sex steroids can modestly increase insulin resistance and reduce glucose tolerance.
What to do
No dose change is usually needed. Monitor glucose when the contraceptive is started.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Canagliflozin-metformin
Frequently asked questions
Can I take Canagliflozin-metformin with Norgestimate?
MediHelp rates the interaction as minor. Canagliflozin-metformin and Norgestimate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Norgestimate, usually given with an estrogen in contraceptives, can slightly reduce glucose tolerance. The effect on diabetes control is usually small.
How serious is the interaction between Canagliflozin-metformin and Norgestimate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed. Monitor glucose when the contraceptive is started.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
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