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Drug interactions

Capecitabine + Olodaterol inhaled

Severity: Minor

Capecitabine and Olodaterol inhaled: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Long-acting beta agonists such as olodaterol may prolong the QT interval or cause hypokalemia, and capecitabine has been linked to QT effects. The combination might modestly increase arrhythmia risk, though systemic exposure from inhalation is low.

What this interaction means in plain words

Capecitabine and Olodaterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive effects on cardiac repolarization, with beta-agonist-induced hypokalemia contributing.

What to do

No routine change is needed, but check potassium and ECG if the patient has cardiac disease or takes other QT-prolonging drugs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Capecitabine with Olodaterol inhaled?

MediHelp rates the interaction as minor. Capecitabine and Olodaterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Long-acting beta agonists such as olodaterol may prolong the QT interval or cause hypokalemia, and capecitabine has been linked to QT effects. The combination might modestly increase arrhythmia risk, though systemic exposure from inhalation is low.

How serious is the interaction between Capecitabine and Olodaterol inhaled?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed, but check potassium and ECG if the patient has cardiac disease or takes other QT-prolonging drugs.

What other medicines interact with Capecitabine?

MediHelp also lists interactions of Capecitabine with, for example, Adenovirus types 4 and 7 live, Arsenic trioxide, Axicabtagene ciloleucel. The full list is on the Capecitabine page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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