Drug interactions
Carbenoxolone + Meloxicam
Severity: Moderate
Carbenoxolone and Meloxicam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbenoxolone causes sodium and water retention with potassium loss, and meloxicam also promotes fluid retention. Together they may worsen hypertension, edema and heart failure, and meloxicam may add renal risk.
What this interaction means in plain words
Carbenoxolone and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Carbenoxolone's mineralocorticoid-like action combines with NSAID-induced renal sodium retention.
What to do
Monitor blood pressure, weight, edema, serum potassium and renal function; avoid in patients with heart failure or uncontrolled hypertension.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Meloxicam
- Ketorolac intranasal + Meloxicam Contraindicated
- Ketorolac + Meloxicam Contraindicated
- Aceclofenac + Meloxicam Major
- Acemetacin + Meloxicam Major
- Acetylsalicylic acid + Meloxicam Major
- Alteplase + Meloxicam Major
Frequently asked questions
Can I take Carbenoxolone with Meloxicam?
MediHelp rates the interaction as moderate. Carbenoxolone and Meloxicam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbenoxolone causes sodium and water retention with potassium loss, and meloxicam also promotes fluid retention. Together they may worsen hypertension, edema and heart failure, and meloxicam may add renal risk.
How serious is the interaction between Carbenoxolone and Meloxicam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, weight, edema, serum potassium and renal function; avoid in patients with heart failure or uncontrolled hypertension.
What other medicines interact with Meloxicam?
MediHelp also lists interactions of Meloxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meloxicam page.
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