Drug interactions
Carbidopa-levodopa + Iloprost inhaled
Severity: Minor
Carbidopa-levodopa and Iloprost inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled iloprost is a vasodilator and can lower systemic blood pressure, and levodopa can cause orthostatic hypotension. Combined use may add to hypotension, though systemic exposure from inhalation is limited.
What this interaction means in plain words
Carbidopa-levodopa and Iloprost inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive hypotensive effects of prostacyclin-mediated vasodilation and levodopa.
What to do
Monitor blood pressure and symptoms of dizziness when starting iloprost. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Carbidopa-levodopa
- Carbidopa-levodopa + Isocarboxazid Contraindicated
- Carbidopa-levodopa + Phenelzine Contraindicated
- Carbidopa-levodopa + Selegiline transdermal Contraindicated
- Carbidopa-levodopa + Tranylcypromine Contraindicated
- Amisulpride + Carbidopa-levodopa Major
- Asenapine + Carbidopa-levodopa Major
Frequently asked questions
Can I take Carbidopa-levodopa with Iloprost inhaled?
MediHelp rates the interaction as minor. Carbidopa-levodopa and Iloprost inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled iloprost is a vasodilator and can lower systemic blood pressure, and levodopa can cause orthostatic hypotension. Combined use may add to hypotension, though systemic exposure from inhalation is limited.
How serious is the interaction between Carbidopa-levodopa and Iloprost inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and symptoms of dizziness when starting iloprost. No routine dose change is needed.
What other medicines interact with Carbidopa-levodopa?
MediHelp also lists interactions of Carbidopa-levodopa with, for example, Isocarboxazid, Phenelzine, Selegiline transdermal. The full list is on the Carbidopa-levodopa page.
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