Drug interactions
Carbonyl iron + Mycophenolate
Severity: Moderate
Carbonyl iron and Mycophenolate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron may reduce mycophenolate absorption, although studies in transplant patients have been inconsistent. A lower mycophenolic acid exposure could in theory increase rejection risk.
What this interaction means in plain words
Carbonyl iron and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Probable binding of mycophenolate to iron in the gut lowers absorption; the mechanism is not fully established.
What to do
Separate iron and mycophenolate dosing by at least 2 hours where possible. Monitor graft function and clinical response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Calcium acetate + Carbonyl iron Moderate
- Calcium carbonate + Carbonyl iron Moderate
- Calcium + Carbonyl iron Moderate
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderate
Frequently asked questions
Can I take Carbonyl iron with Mycophenolate?
MediHelp rates the interaction as moderate. Carbonyl iron and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron may reduce mycophenolate absorption, although studies in transplant patients have been inconsistent. A lower mycophenolic acid exposure could in theory increase rejection risk.
How serious is the interaction between Carbonyl iron and Mycophenolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate iron and mycophenolate dosing by at least 2 hours where possible. Monitor graft function and clinical response.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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