Drug interactions
Aluminum hydroxide + Carbonyl iron
Severity: Moderate
Aluminum hydroxide and Carbonyl iron: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids reduce gastric acidity and can bind iron, lowering the absorption of oral iron. Over time this may diminish response to iron supplementation.
What this interaction means in plain words
Aluminum hydroxide and Carbonyl iron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Carbonyl iron belongs to Miscellaneous.
Why it happens
Higher gastric pH and binding reduce iron dissolution and absorption.
What to do
Separate iron from antacids by at least 2 hours. Monitor hemoglobin and ferritin if antacids are used often.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Carbonyl iron?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Carbonyl iron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antacids reduce gastric acidity and can bind iron, lowering the absorption of oral iron. Over time this may diminish response to iron supplementation.
How serious is the interaction between Aluminum hydroxide and Carbonyl iron?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate iron from antacids by at least 2 hours. Monitor hemoglobin and ferritin if antacids are used often.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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