Drug interactions
Carteolol + Fingolimod
Severity: Moderate
Carteolol and Fingolimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ophthalmic carteolol is a beta-blocker with some systemic absorption, and fingolimod slows heart rate at initiation. Together they may raise the risk of bradycardia and AV block, although systemic exposure from eye drops is lower than with oral beta-blockers.
What this interaction means in plain words
Carteolol and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive negative chronotropic and dromotropic effects.
What to do
Obtain a baseline ECG and monitor heart rate for at least 6 hours after the first fingolimod dose. Consider an alternative non-beta-blocker glaucoma agent.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Carteolol with Fingolimod?
MediHelp rates the interaction as moderate. Carteolol and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ophthalmic carteolol is a beta-blocker with some systemic absorption, and fingolimod slows heart rate at initiation. Together they may raise the risk of bradycardia and AV block, although systemic exposure from eye drops is lower than with oral beta-blockers.
How serious is the interaction between Carteolol and Fingolimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor heart rate for at least 6 hours after the first fingolimod dose. Consider an alternative non-beta-blocker glaucoma agent.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Pimozide. The full list is on the Fingolimod page.
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