Drug interactions
Carvedilol + Dabigatran etexilate
Severity: Minor
Carvedilol and Dabigatran etexilate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carvedilol inhibits P-glycoprotein and could modestly raise dabigatran exposure. The effect is generally small, but it could be relevant in patients with reduced renal function.
What this interaction means in plain words
Carvedilol and Dabigatran etexilate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carvedilol belongs to Cardiovascular; Dabigatran etexilate belongs to Cardiovascular.
Why it happens
Inhibition of intestinal P-glycoprotein efflux, slightly increasing dabigatran etexilate absorption.
What to do
No routine dose adjustment is needed. Monitor renal function and watch for bleeding in at-risk patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Other interactions of Carvedilol
Frequently asked questions
Can I take Carvedilol with Dabigatran etexilate?
MediHelp rates the interaction as minor. Carvedilol and Dabigatran etexilate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Carvedilol inhibits P-glycoprotein and could modestly raise dabigatran exposure. The effect is generally small, but it could be relevant in patients with reduced renal function.
How serious is the interaction between Carvedilol and Dabigatran etexilate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose adjustment is needed. Monitor renal function and watch for bleeding in at-risk patients.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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