Drug interactions
Carvedilol + Hydrochlorothiazide-telmisartan
Severity: Moderate
Carvedilol and Hydrochlorothiazide-telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carvedilol with an ARB/thiazide combination can cause additive hypotension, dizziness and bradycardia. Beta-blockers may slightly raise potassium.
What this interaction means in plain words
Carvedilol and Hydrochlorothiazide-telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carvedilol belongs to Cardiovascular; Hydrochlorothiazide-telmisartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects from RAAS blockade, diuresis and combined alpha-1/beta-adrenergic blockade.
What to do
Monitor blood pressure, heart rate and serum potassium when starting or titrating; separate dose increases and adjust if orthostatic symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Carvedilol
Frequently asked questions
Can I take Carvedilol with Hydrochlorothiazide-telmisartan?
MediHelp rates the interaction as moderate. Carvedilol and Hydrochlorothiazide-telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carvedilol with an ARB/thiazide combination can cause additive hypotension, dizziness and bradycardia. Beta-blockers may slightly raise potassium.
How serious is the interaction between Carvedilol and Hydrochlorothiazide-telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium when starting or titrating; separate dose increases and adjust if orthostatic symptoms occur.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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