Drug interactions
Carvedilol + Terazosin
Severity: Moderate
Carvedilol and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carvedilol has its own alpha-1 blocking activity, so combining it with terazosin adds to vasodilation and hypotension. Orthostatic hypotension and syncope are more likely, especially at initiation.
What this interaction means in plain words
Carvedilol and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carvedilol belongs to Cardiovascular; Terazosin belongs to Genitourinary.
Why it happens
Additive alpha-1 adrenergic blockade and beta-blockade causing pharmacodynamic hypotension.
What to do
Avoid combining where possible, or introduce each drug at a low dose and titrate slowly. Monitor orthostatic blood pressure and symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Carvedilol
Frequently asked questions
Can I take Carvedilol with Terazosin?
MediHelp rates the interaction as moderate. Carvedilol and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carvedilol has its own alpha-1 blocking activity, so combining it with terazosin adds to vasodilation and hypotension. Orthostatic hypotension and syncope are more likely, especially at initiation.
How serious is the interaction between Carvedilol and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible, or introduce each drug at a low dose and titrate slowly. Monitor orthostatic blood pressure and symptoms.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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