Drug interactions
Cefadroxil + Ketorolac
Severity: Minor
Cefadroxil and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are organic acids eliminated by renal tubular secretion, so competition may modestly raise ketorolac or cefadroxil concentrations. This is unlikely to be clinically important with short courses in patients with normal renal function.
What this interaction means in plain words
Cefadroxil and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefadroxil belongs to Anti Bacterial; Ketorolac belongs to Musculoskeletal.
Why it happens
Competition for renal tubular organic anion transporters reduces tubular secretion.
What to do
No dose change is usually needed; monitor renal function in patients with kidney impairment or on prolonged therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Cefadroxil
- Amikacin + Cefadroxil Moderate
- Avelumab + Cefadroxil Moderate
- Balstilimab + Cefadroxil Moderate
- Bcg vaccine live + Cefadroxil Moderate
- Cefadroxil + Cholera vaccine Moderate
- Cefadroxil + Gentamicin Moderate
Frequently asked questions
Can I take Cefadroxil with Ketorolac?
MediHelp rates the interaction as minor. Cefadroxil and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are organic acids eliminated by renal tubular secretion, so competition may modestly raise ketorolac or cefadroxil concentrations. This is unlikely to be clinically important with short courses in patients with normal renal function.
How serious is the interaction between Cefadroxil and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor renal function in patients with kidney impairment or on prolonged therapy.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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