Drug interactions
Cefadroxil + Temocillin
Severity: Minor
Cefadroxil and Temocillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are beta-lactams cleared by the kidney, so they could modestly compete for tubular secretion. No clinically significant interaction is documented, and the combination offers little therapeutic rationale. Any exposure increase is expected to be small.
What this interaction means in plain words
Cefadroxil and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular secretion of beta-lactams via organic anion transporters.
What to do
No specific action is generally needed. Adjust doses for renal impairment as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefadroxil
- Amikacin + Cefadroxil Moderate
- Avelumab + Cefadroxil Moderate
- Balstilimab + Cefadroxil Moderate
- Bcg vaccine live + Cefadroxil Moderate
- Cefadroxil + Cholera vaccine Moderate
- Cefadroxil + Gentamicin Moderate
Frequently asked questions
Can I take Cefadroxil with Temocillin?
MediHelp rates the interaction as minor. Cefadroxil and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are beta-lactams cleared by the kidney, so they could modestly compete for tubular secretion. No clinically significant interaction is documented, and the combination offers little therapeutic rationale. Any exposure increase is expected to be small.
How serious is the interaction between Cefadroxil and Temocillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is generally needed. Adjust doses for renal impairment as usual.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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