Drug interactions
Cefamandole + Flurbiprofen
Severity: Minor
Cefamandole and Flurbiprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are organic acids eliminated partly by renal tubular secretion, so flurbiprofen levels could rise slightly. The clinical significance is thought to be small.
What this interaction means in plain words
Cefamandole and Flurbiprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for renal tubular anion secretion may reduce flurbiprofen clearance.
What to do
No action is usually required; watch for NSAID adverse effects such as GI upset in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Frequently asked questions
Can I take Cefamandole with Flurbiprofen?
MediHelp rates the interaction as minor. Cefamandole and Flurbiprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are organic acids eliminated partly by renal tubular secretion, so flurbiprofen levels could rise slightly. The clinical significance is thought to be small.
How serious is the interaction between Cefamandole and Flurbiprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is usually required; watch for NSAID adverse effects such as GI upset in patients with renal impairment.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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