Drug interactions
Celiprolol + Eprosartan-hydrochlorothiazide
Severity: Minor
Celiprolol and Eprosartan-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol adds to the blood pressure lowering of eprosartan and hydrochlorothiazide, which is often intended but may cause hypotension or bradycardia. Hydrochlorothiazide can reduce the oral absorption and exposure of celiprolol, possibly weakening its effect.
What this interaction means in plain words
Celiprolol and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive pharmacodynamics, plus reduced intestinal absorption of celiprolol in the presence of hydrochlorothiazide.
What to do
Monitor blood pressure and heart rate after starting or changing therapy. Adjust the celiprolol dose if response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Celiprolol with Eprosartan-hydrochlorothiazide?
MediHelp rates the interaction as minor. Celiprolol and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Celiprolol adds to the blood pressure lowering of eprosartan and hydrochlorothiazide, which is often intended but may cause hypotension or bradycardia. Hydrochlorothiazide can reduce the oral absorption and exposure of celiprolol, possibly weakening its effect.
How serious is the interaction between Celiprolol and Eprosartan-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate after starting or changing therapy. Adjust the celiprolol dose if response is inadequate.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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