Drug interactions
Celiprolol + Hydralazine
Severity: Minor
Celiprolol and Hydralazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol is a beta-blocker with antihypertensive activity and hydralazine is a direct vasodilator, so combined use lowers blood pressure more than either alone. This is often intentional, and beta-blockade also blunts the reflex tachycardia caused by hydralazine.
What this interaction means in plain words
Celiprolol and Hydralazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Complementary pharmacodynamic antihypertensive effects through beta-blockade and direct arteriolar vasodilation.
What to do
Monitor blood pressure and heart rate when starting or adjusting either drug, and titrate doses to the blood pressure target.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydralazine
- Amifostine + Hydralazine Major
- Aceclofenac + Hydralazine Moderate
- Acemetacin + Hydralazine Moderate
- Aldesleukin + Hydralazine Moderate
- Avanafil + Hydralazine Moderate
- Benzphetamine + Hydralazine Moderate
Frequently asked questions
Can I take Celiprolol with Hydralazine?
MediHelp rates the interaction as minor. Celiprolol and Hydralazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Celiprolol is a beta-blocker with antihypertensive activity and hydralazine is a direct vasodilator, so combined use lowers blood pressure more than either alone. This is often intentional, and beta-blockade also blunts the reflex tachycardia caused by hydralazine.
How serious is the interaction between Celiprolol and Hydralazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting either drug, and titrate doses to the blood pressure target.
What other medicines interact with Hydralazine?
MediHelp also lists interactions of Hydralazine with, for example, Amifostine, Aceclofenac, Acemetacin. The full list is on the Hydralazine page.
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