Drug interactions
Celiprolol + Hydrochlorothiazide-telmisartan
Severity: Moderate
Celiprolol and Hydrochlorothiazide-telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol is a beta-blocker, so the combination has additive blood pressure lowering, which is often intended. Hydrochlorothiazide can reduce celiprolol absorption, and the combination can affect potassium and glucose handling. Telmisartan adds the fetal risk of RAAS blockade in pregnancy.
What this interaction means in plain words
Celiprolol and Hydrochlorothiazide-telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antihypertensive effects, and reduced gastrointestinal absorption of celiprolol in the presence of hydrochlorothiazide.
What to do
Monitor blood pressure and heart rate and adjust doses to response. Check serum potassium periodically and avoid use in pregnancy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Celiprolol with Hydrochlorothiazide-telmisartan?
MediHelp rates the interaction as moderate. Celiprolol and Hydrochlorothiazide-telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker, so the combination has additive blood pressure lowering, which is often intended. Hydrochlorothiazide can reduce celiprolol absorption, and the combination can affect potassium and glucose handling. Telmisartan adds the fetal risk of RAAS blockade in pregnancy.
How serious is the interaction between Celiprolol and Hydrochlorothiazide-telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate and adjust doses to response. Check serum potassium periodically and avoid use in pregnancy.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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