Drug interactions
Celiprolol + Nifedipine
Severity: Moderate
Celiprolol and Nifedipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure, so the combination gives additive antihypertensive effect and can cause hypotension. Celiprolol is a beta-blocker with mild vasodilating properties; combining a beta-blocker with a dihydropyridine is common and generally well tolerated.
What this interaction means in plain words
Celiprolol and Nifedipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic blood pressure lowering through vasodilation and beta-blockade.
What to do
Monitor blood pressure and heart rate when starting or adjusting either drug. Lower the dose of one agent if symptomatic hypotension or marked tachycardia or bradycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nifedipine
Frequently asked questions
Can I take Celiprolol with Nifedipine?
MediHelp rates the interaction as moderate. Celiprolol and Nifedipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure, so the combination gives additive antihypertensive effect and can cause hypotension. Celiprolol is a beta-blocker with mild vasodilating properties; combining a beta-blocker with a dihydropyridine is common and generally well tolerated.
How serious is the interaction between Celiprolol and Nifedipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting either drug. Lower the dose of one agent if symptomatic hypotension or marked tachycardia or bradycardia occurs.
What other medicines interact with Nifedipine?
MediHelp also lists interactions of Nifedipine with, for example, Amifostine, Amlodipine-benazepril, Apalutamide. The full list is on the Nifedipine page.
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