Drug interactions
Celiprolol + Salbutamol
Severity: Moderate
Celiprolol and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol is a beta-blocker with beta-2 partial agonist activity and relative beta-1 selectivity, and it can blunt the bronchodilator effect of salbutamol. This may reduce asthma control, although it is less pronounced than with non-selective agents.
What this interaction means in plain words
Celiprolol and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism at beta-adrenergic receptors.
What to do
Monitor respiratory status and peak flow, and avoid celiprolol in patients with significant asthma where alternatives exist.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Frequently asked questions
Can I take Celiprolol with Salbutamol?
MediHelp rates the interaction as moderate. Celiprolol and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker with beta-2 partial agonist activity and relative beta-1 selectivity, and it can blunt the bronchodilator effect of salbutamol. This may reduce asthma control, although it is less pronounced than with non-selective agents.
How serious is the interaction between Celiprolol and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory status and peak flow, and avoid celiprolol in patients with significant asthma where alternatives exist.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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