Drug interactions
Celiprolol + Salmeterol
Severity: Moderate
Celiprolol and Salmeterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol is a beta-blocker that can antagonize the bronchodilator effect of salmeterol. It is cardioselective with some beta-2 partial agonist activity, so the risk is lower, but loss of asthma or COPD control is still possible.
What this interaction means in plain words
Celiprolol and Salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism at beta-adrenergic receptors.
What to do
Monitor respiratory symptoms and lung function when combining. Use an alternative non-beta-blocker antihypertensive in patients with asthma.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salmeterol
- Ritonavir + Salmeterol Contraindicated
- Salmeterol + Saquinavir Contraindicated
- Amitriptyline + Salmeterol Major
- Arformoterol + Salmeterol Major
- Atazanavir + Salmeterol Major
- Budesonide-formoterol + Salmeterol Major
Frequently asked questions
Can I take Celiprolol with Salmeterol?
MediHelp rates the interaction as moderate. Celiprolol and Salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker that can antagonize the bronchodilator effect of salmeterol. It is cardioselective with some beta-2 partial agonist activity, so the risk is lower, but loss of asthma or COPD control is still possible.
How serious is the interaction between Celiprolol and Salmeterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory symptoms and lung function when combining. Use an alternative non-beta-blocker antihypertensive in patients with asthma.
What other medicines interact with Salmeterol?
MediHelp also lists interactions of Salmeterol with, for example, Ritonavir, Saquinavir, Amitriptyline. The full list is on the Salmeterol page.
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