Drug interactions
Celiprolol + Timolol
Severity: Moderate
Celiprolol and Timolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are beta-blockers, so combining them duplicates therapy without added benefit. This raises the risk of bradycardia, hypotension and AV conduction block. Systemic timolol exposure from eye drops is lower but can still matter in susceptible patients.
What this interaction means in plain words
Celiprolol and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic receptor blockade (pharmacodynamic duplication).
What to do
Avoid combining two beta-blockers; use a single agent. If both are unavoidable, monitor heart rate, blood pressure and ECG.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Frequently asked questions
Can I take Celiprolol with Timolol?
MediHelp rates the interaction as moderate. Celiprolol and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are beta-blockers, so combining them duplicates therapy without added benefit. This raises the risk of bradycardia, hypotension and AV conduction block. Systemic timolol exposure from eye drops is lower but can still matter in susceptible patients.
How serious is the interaction between Celiprolol and Timolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining two beta-blockers; use a single agent. If both are unavoidable, monitor heart rate, blood pressure and ECG.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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