Drug interactions
Cephaloridine + Foscarnet
Severity: Moderate
Cephaloridine and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cephaloridine is a nephrotoxic cephalosporin that is no longer in clinical use. Combined with foscarnet it would be expected to increase the risk of kidney injury.
What this interaction means in plain words
Cephaloridine and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Predicted additive nephrotoxicity (proximal tubular injury) from both drugs.
What to do
Avoid the combination and use a non-nephrotoxic antibacterial. If it cannot be avoided, monitor serum creatinine and electrolytes closely.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Cephaloridine with Foscarnet?
MediHelp rates the interaction as moderate. Cephaloridine and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cephaloridine is a nephrotoxic cephalosporin that is no longer in clinical use. Combined with foscarnet it would be expected to increase the risk of kidney injury.
How serious is the interaction between Cephaloridine and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-nephrotoxic antibacterial. If it cannot be avoided, monitor serum creatinine and electrolytes closely.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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