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Drug interactions

Chlorpropamide + Halofenate

Severity: Minor

Chlorpropamide and Halofenate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Halofenate is an investigational lipid- and uric acid-lowering agent that has been associated with enhanced effects of sulfonylureas. Information is limited and it is not marketed widely.

What this interaction means in plain words

Chlorpropamide and Halofenate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Mechanism unknown; possible displacement from protein binding or additive glucose-lowering effect.

What to do

If both drugs are given, monitor blood glucose and adjust the chlorpropamide dose as needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chlorpropamide with Halofenate?

MediHelp rates the interaction as minor. Chlorpropamide and Halofenate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Halofenate is an investigational lipid- and uric acid-lowering agent that has been associated with enhanced effects of sulfonylureas. Information is limited and it is not marketed widely.

How serious is the interaction between Chlorpropamide and Halofenate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If both drugs are given, monitor blood glucose and adjust the chlorpropamide dose as needed.

What other medicines interact with Chlorpropamide?

MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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