Drug interactions
Chlorpropamide + Tongkat ali
Severity: Minor
Chlorpropamide and Tongkat ali: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tongkat ali (Eurycoma longifolia) has reported glucose-lowering activity in experimental settings. Taken with chlorpropamide, which has a long half-life, it could theoretically add to hypoglycemia risk.
What this interaction means in plain words
Chlorpropamide and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic effect; the mechanism is not firmly established and the supporting data are limited.
What to do
Advise patients to report use of the herbal product and monitor capillary blood glucose after starting it. Lower the chlorpropamide dose if low readings occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlorpropamide
Frequently asked questions
Can I take Chlorpropamide with Tongkat ali?
MediHelp rates the interaction as minor. Chlorpropamide and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tongkat ali (Eurycoma longifolia) has reported glucose-lowering activity in experimental settings. Taken with chlorpropamide, which has a long half-life, it could theoretically add to hypoglycemia risk.
How serious is the interaction between Chlorpropamide and Tongkat ali?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report use of the herbal product and monitor capillary blood glucose after starting it. Lower the chlorpropamide dose if low readings occur.
What other medicines interact with Chlorpropamide?
MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.
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