Drug interactions
Chlorthalidone + Cornsilk
Severity: Minor
Chlorthalidone and Cornsilk: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cornsilk has reputed diuretic activity and may increase potassium loss when taken with chlorthalidone. The evidence is theoretical.
What this interaction means in plain words
Chlorthalidone and Cornsilk have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive diuretic and kaliuretic effect; mechanism not firmly established.
What to do
Advise against routine use of cornsilk supplements, and check potassium if used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Chlorthalidone and Cornsilk, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Chlorthalidone
Frequently asked questions
Can I take Chlorthalidone with Cornsilk?
MediHelp rates the interaction as minor. Chlorthalidone and Cornsilk have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cornsilk has reputed diuretic activity and may increase potassium loss when taken with chlorthalidone. The evidence is theoretical.
How serious is the interaction between Chlorthalidone and Cornsilk?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise against routine use of cornsilk supplements, and check potassium if used regularly.
What other medicines interact with Chlorthalidone?
MediHelp also lists interactions of Chlorthalidone with, for example, Amifostine, Atenolol-chlorthalidone, Candesartan-hydrochlorothiazide. The full list is on the Chlorthalidone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
