Drug reference

chlorthalidone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Cardiovascular (Diuretics)

Mechanism of action

Similar to thiazide diuretics; inhibits sodium and chloride reabsorption in cortical diluting segment of ascending loop of Henle, causing increased excretion of sodium, chloride, and water

Common side effects

  • Constipation
  • Dizziness
  • Hypotension
  • Photosensitivity
  • Electrolyte abnormalities
  • Blurred Vision
  • Spasticity

Contraindications

  • Documented hypersensitivity to chlorthalidone or sulfonamides

Related conditions

Frequently asked questions

What drug class is chlorthalidone?

chlorthalidone belongs to: Cardiovascular.

How does chlorthalidone work?

Similar to thiazide diuretics; inhibits sodium and chloride reabsorption in cortical diluting segment of ascending loop of Henle, causing increased excretion of sodium, chloride, and water

What are the common side effects of chlorthalidone?

Constipation, Dizziness, Hypotension, Photosensitivity, Electrolyte abnormalities, Blurred Vision, Spasticity

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