Drug interactions
Cholera vaccine + Daunorubicin
Severity: Minor
Cholera vaccine and Daunorubicin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Daunorubicin causes myelosuppression and immune suppression, which may reduce the response to cholera vaccine. Protection for travelers or patients in endemic areas may be weaker.
What this interaction means in plain words
Cholera vaccine and Daunorubicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Cytotoxic myelosuppression and lymphopenia blunt the immune response to vaccine antigens.
What to do
Give the vaccine at least 2 weeks before chemotherapy if possible; otherwise stress hygiene precautions and consider revaccination after immune recovery. Note that live oral cholera vaccine is generally avoided during chemotherapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cholera vaccine and Daunorubicin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Daunorubicin
- Adenovirus types 4 and 7 live + Daunorubicin Contraindicated
- Belatacept + Daunorubicin Major
- Cyclosporin + Daunorubicin Major
- Daunorubicin + Dengue vaccine Major
- Daunorubicin + Etrasimod Major
- Daunorubicin + Fingolimod Major
Frequently asked questions
Can I take Cholera vaccine with Daunorubicin?
MediHelp rates the interaction as minor. Cholera vaccine and Daunorubicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Daunorubicin causes myelosuppression and immune suppression, which may reduce the response to cholera vaccine. Protection for travelers or patients in endemic areas may be weaker.
How serious is the interaction between Cholera vaccine and Daunorubicin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the vaccine at least 2 weeks before chemotherapy if possible; otherwise stress hygiene precautions and consider revaccination after immune recovery. Note that live oral cholera vaccine is generally avoided during chemotherapy.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclosporin. The full list is on the Daunorubicin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
