Drug interactions
Cholera vaccine + Triamcinolone
Severity: Moderate
Cholera vaccine and Triamcinolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Immunosuppressive corticosteroid doses can blunt the antibody response to vaccines. Injectable triamcinolone with significant systemic exposure may therefore reduce protection from the cholera vaccine.
What this interaction means in plain words
Cholera vaccine and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Corticosteroids suppress lymphocyte function and antibody production, reducing vaccine immunogenicity.
What to do
Where possible, vaccinate before starting or after stopping immunosuppressive corticosteroid doses; consider revaccination or checking response if given during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triamcinolone
- Smallpox vaccine live + Triamcinolone Contraindicated
- Triamcinolone + Zoster vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Triamcinolone Major
- Aldesleukin + Triamcinolone Major
- Atazanavir + Triamcinolone Major
- Axicabtagene ciloleucel + Triamcinolone Major
Frequently asked questions
Can I take Cholera vaccine with Triamcinolone?
MediHelp rates the interaction as moderate. Cholera vaccine and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Immunosuppressive corticosteroid doses can blunt the antibody response to vaccines. Injectable triamcinolone with significant systemic exposure may therefore reduce protection from the cholera vaccine.
How serious is the interaction between Cholera vaccine and Triamcinolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, vaccinate before starting or after stopping immunosuppressive corticosteroid doses; consider revaccination or checking response if given during therapy.
What other medicines interact with Triamcinolone?
MediHelp also lists interactions of Triamcinolone with, for example, Smallpox vaccine live, Zoster vaccine live, Adenovirus types 4 and 7 live. The full list is on the Triamcinolone page.
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