Drug interactions
Choline magnesium trisalicylate + Enoxaparin
Severity: Moderate
Choline magnesium trisalicylate and Enoxaparin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This non-acetylated salicylate has weaker antiplatelet activity than aspirin but can still modestly raise bleeding risk, especially at high doses. Combined with enoxaparin, caution is needed with gastrointestinal or procedural bleeding risk.
What this interaction means in plain words
Choline magnesium trisalicylate and Enoxaparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hemostatic impairment from salicylate effects on platelets and mucosa plus enoxaparin anticoagulation.
What to do
Monitor for bleeding and hemoglobin, and use the lowest effective salicylate dose. Consider paracetamol as an alternative analgesic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Choline magnesium trisalicylate with Enoxaparin?
MediHelp rates the interaction as moderate. Choline magnesium trisalicylate and Enoxaparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. This non-acetylated salicylate has weaker antiplatelet activity than aspirin but can still modestly raise bleeding risk, especially at high doses. Combined with enoxaparin, caution is needed with gastrointestinal or procedural bleeding risk.
How serious is the interaction between Choline magnesium trisalicylate and Enoxaparin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and hemoglobin, and use the lowest effective salicylate dose. Consider paracetamol as an alternative analgesic.
What other medicines interact with Enoxaparin?
MediHelp also lists interactions of Enoxaparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Enoxaparin page.
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