Drug interactions
Cinnamon + Glyburide-metformin
Severity: Minor
Cinnamon and Glyburide-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cinnamon supplements may lower blood glucose modestly and could add to the effects of glyburide and metformin, raising the possibility of hypoglycemia. Evidence of clinical significance is limited.
What this interaction means in plain words
Cinnamon and Glyburide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive glucose-lowering through improved insulin sensitivity and slowed carbohydrate absorption.
What to do
Monitor blood glucose if cinnamon supplements are taken regularly and adjust glyburide if lows occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glyburide-metformin
Frequently asked questions
Can I take Cinnamon with Glyburide-metformin?
MediHelp rates the interaction as minor. Cinnamon and Glyburide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cinnamon supplements may lower blood glucose modestly and could add to the effects of glyburide and metformin, raising the possibility of hypoglycemia. Evidence of clinical significance is limited.
How serious is the interaction between Cinnamon and Glyburide-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if cinnamon supplements are taken regularly and adjust glyburide if lows occur.
What other medicines interact with Glyburide-metformin?
MediHelp also lists interactions of Glyburide-metformin with, for example, Bosentan, Cholic acid, Clarithromycin. The full list is on the Glyburide-metformin page.
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