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Drug interactions

Cinnamon + Naproxen

Severity: Minor

Cinnamon and Naproxen: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cinnamon, particularly cassia, contains coumarin and may have mild antiplatelet effects. Combined with naproxen this could slightly raise bleeding risk, but clinical evidence is scarce.

What this interaction means in plain words

Cinnamon and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive antiplatelet or anticoagulant effect; the mechanism is not firmly established.

What to do

Dietary amounts need no action. Advise patients taking concentrated cinnamon supplements with naproxen to report unusual bruising or bleeding.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cinnamon with Naproxen?

MediHelp rates the interaction as minor. Cinnamon and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cinnamon, particularly cassia, contains coumarin and may have mild antiplatelet effects. Combined with naproxen this could slightly raise bleeding risk, but clinical evidence is scarce.

How serious is the interaction between Cinnamon and Naproxen?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Dietary amounts need no action. Advise patients taking concentrated cinnamon supplements with naproxen to report unusual bruising or bleeding.

What other medicines interact with Naproxen?

MediHelp also lists interactions of Naproxen with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Naproxen page.

Full monographs, dosing and an interaction checker in the MediHelp app

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